Copyright
©2007 Baishideng Publishing Group Co.
World J Gastroenterol. Mar 21, 2007; 13(11): 1715-1722
Published online Mar 21, 2007. doi: 10.3748/wjg.v13.i11.1715
Published online Mar 21, 2007. doi: 10.3748/wjg.v13.i11.1715
Table 2 Clinical characteristics, thyroid biochemistry, thyroid serology, and HLA-DQ data of patients with both Hashimoto’s thyroiditis and coeliac disease compared to patients with Hashimoto’s thyroiditis only
| Characteristics | Patients with only | Patients with both coeliac disease | P |
| Hashimoto’s thyroiditis | and Hashimoto’s thyroirditis | ||
| n = 99 | n = 27 | ||
| Presence of goiter, n (%) | 19 (19) | 4 (15) | > 0.05 |
| Presence of autoimmune diseases, n (%) | 11 (11) | 7 (26) | < 0.01 |
| Thyroid function test | |||
| mean ± SD TSH (normal 0.30-4.00 mU/L) | 24 (± 7.6) | 16 (± 5.8) | < 0.05 |
| mean ± SD Free T4 (normal 11-22 pmol/L) | 10 (± 4.1) | 12 (± 5.2) | > 0.05 |
| Positive thyroid serological tests, n (%) | |||
| Thyroglobulin (TG) | 35 (36) | 11 (41) | > 0.05 |
| Thyroid peroxidase (TPO) | 93 (94) | 25 (92) | > 0.05 |
| HLA-DQ 2 and/or -DQ8, n (%) | 53 (53) | 27 (100) | < 0.01 |
| DQ2 heterozygote | 30 (30) | 20 (74) | < 0.01 |
| DQ2 homozygote | 1 (1) | 3 (11) | < 0.01 |
| DQ8 heterozygote | 22 (22) | - | - |
| Combined DQ2 & DQ8 | 10 (10) | 4 (15) | > 0.05 |
- Citation: Hadithi M, de Boer H, Meijer JW, Willekens F, Kerckhaert JA, Heijmans R, Peña AS, Stehouwer CD, Mulder CJ. Coeliac disease in Dutch patients with Hashimoto’s thyroiditis and vice versa. World J Gastroenterol 2007; 13(11): 1715-1722
- URL: https://www.wjgnet.com/1007-9327/full/v13/i11/1715.htm
- DOI: https://dx.doi.org/10.3748/wjg.v13.i11.1715