Aquaporin-8 expression is reduced in ileum and induced in colon of patients with ulcerative colitis

Table 6 Allelic contribution of AQP8 SNPs

SNP		n VIC	% VIC	n FAM	% FAM	n both	% both	P-Value	χ2
AQP8-A212T		G	G	A	A	G/A	G/A
GCC -> ACC	UC	210	95.5	0	0.0	9	4.1	0.57	0.33
	CD	166	91.7	0	0.0	9	5.0	0.98	0.00
	Co	232	92.8	0	0.0	14	5.6
AQP8-A260P		G	G	C	C	C/G	C/G
GCT -> CCT	UC	94	42.7	33	15.0	78	35.5	0.26	2.66
	CD	56	30.9	26	14.4	83	45.9	0.46	1.55
	Co	93	37.2	43	17.2	107	42.8
APQ8-R261Q		G	G	A	A	G/A	G/A
CGG -> CAG	UC	205	93.2	0	0.0	13	5.9	0.62	0.97
	CD	159	87.8	1	0.6	9	5.0	0.97	0.07
	Co	214	85.6	1	0.4	13	5.2