Aquaporin-8 expression is reduced in ileum and induced in colon of patients with ulcerative colitis

Table 5 Aquaporin gene expression and regulation in IBD

Gene	Controlexpression ileum	FC CD	FC UC	Controlexpression colon	FC CD	FC UC
AQP1	181	1.7	1.7	165	-2.0	-1.6
AQP3	473	1.9	1.5	352	-1.4	-3.2
AQP8	575	-8.6	-9.8	438	4.3	3.0
AQP11	510	1.2	1.0	409	-1.9	-2.0

List of all AQPs whose transcripts were increased or decreased (shown as minus) in Crohns Disease (CD) or Ulcerative Colitis (UC) samples compared with control specimens. The control expression values are given for the terminal ileum and the colon. Genes with an average difference intensity of 50 are considered as significantly expressed in the given cell type. The fold change (FC) of gene expression between controls and patient groups is indicated. No transcripts for AQP0, AQP2, AQP4, AQP5, AQP6, AQP7 and AQP9 could be detected. AQP10 and AQP12 are not represented on the used arrays.