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©2007 Baishideng Publishing Group Co.
World J Gastroenterol. Mar 21, 2007; 13(11): 1687-1695
Published online Mar 21, 2007. doi: 10.3748/wjg.v13.i11.1687
Published online Mar 21, 2007. doi: 10.3748/wjg.v13.i11.1687
Table 4 Selection of differentially expressed genes located in IBD candidate loci
IBDcandidatelocus/Gene | Controlexpressionileum | FCCD | FCUC | Controlexpressioncolon | FCCD | FCUC |
Chr. 16q11-12 | ||||||
MMP2 | 267 | 1.5 | -1.1 | 220 | 1.5 | 3.7 |
TM4SF11 | 194 | 1.3 | 1.0 | 151 | -2.1 | -1.7 |
SIAH1 | 208 | 1.6 | 1.2 | 156 | 3.5 | 1.3 |
MT1G | 3053 | -1.1 | 1.2 | 2356 | -1.7 | -2.0 |
NETO2 | 49 | -1.6 | -1.7 | 61 | 2.5 | 1.4 |
Chr. 12q13 | ||||||
DGKA | 427 | -1.5 | 1.0 | 342 | -2.3 | -2.6 |
MYO1A | 1008 | 1.1 | 1.1 | 811 | -3.5 | -4.3 |
Chr. 5q32 | ||||||
SPARC | 76 | 2.6 | 1.5 | 104 | 2.0 | 2.6 |
TGFBI | 236 | 2.0 | 1.0 | 356 | 1.5 | 2.5 |
CAMLG | 93 | 2.5 | 1.4 | 91 | 2.1 | 1.4 |
TCF7 | 357 | -2.0 | -1.2 | 279 | -1.2 | -1.6 |
SLC35A4 | 535 | -1.5 | -1.5 | 638 | -2.3 | -1.5 |
SEC24A | 221 | 2.3 | 1.1 | 211 | 1.7 | 1.1 |
SLC26A2 | 302 | 2.3 | -2.5 | 388 | 6.5 | -7.5 |
EGR1 | 256 | 2.3 | 1.1 | 180 | 17.1 | 3.0 |
PACAP | 150 | -2.8 | -1.7 | 138 | -1.6 | 2.0 |
Chr. 19p13 | ||||||
AES | 222 | -2.1 | -1,1 | 257 | -2.5 | -2.3 |
MAP2K2 | 420 | -2.0 | -1,1 | 627 | -2.1 | -5.7 |
Chr. 1p36 | ||||||
CDC42 | 1428 | 1.1 | -1.2 | 1429 | 2.0 | -1.9 |
MFN2 | 304 | -1,1 | 1.0 | 367 | -3.0 | -2.5 |
C1QA | 336 | 1.1 | 1.1 | 373 | -1.6 | -2.5 |
Chr. 16p12 | ||||||
MIR16 | 201 | -1.7 | -1.1 | 277 | -3.0 | -1.2 |
AQP8 | 575 | -8.6 | -9.8 | 438 | 4.3 | 3.0 |
MT1G | 3053 | -1.1 | 1.2 | 2356 | -1.7 | -2.0 |
LITAF | 500 | -1.2 | -1.2 | 670 | 1.9 | 2.1 |
PRKCB1 | 157 | -2.0 | 1.4 | 95 | 1.1 | -1.2 |
USP7 | 184 | 1.6 | -1.3 | 192 | 2.0 | -1.1 |
Chr. 7q11 | ||||||
WBSCR22 | 172 | -1.7 | -1.1 | 207 | -1.9 | -2.3 |
POR | 213 | -2.1 | 1.0 | 172 | -2.3 | -4.9 |
SEMA3C | 79 | 1.1 | 1.0 | 70 | 2.3 | 1.9 |
CLDN3 | 386 | -1.4 | -1.2 | 618 | -2.6 | -6.5 |
WBSCR20A | 323 | -1.6 | 1.0 | 281 | -2.0 | -1.7 |
TMPIT | 928 | 1.1 | 1.1 | 893 | -2.3 | -2.3 |
CLDN4 | 150 | 1.1 | 1.0 | 232 | -1.4 | -2.3 |
CD36 | 153 | 2.8 | 1.3 | 127 | 2.3 | 1.1 |
HSPB1 | 376 | -3.2 | -2.3 | 493 | -1.9 | -1.5 |
Chr. 4q25 | ||||||
ELOVL6 | 112 | 1.2 | -1.6 | 332 | 2.1 | 1.6 |
ENPEP | 578 | 1.7 | 1.6 | 533 | 1.1 | -11.3 |
T2BP | 322 | 1.2 | 1.1 | 224 | 2.8 | 1.4 |
SYNPO2 | 242 | 2.3 | 1.3 | 160 | 2.5 | 1.1 |
SEC24B | 105 | 2.0 | 1.6 | 161 | 1.6 | 1.1 |
Chr. 3p21 | ||||||
ACY1 | 744 | 1.1 | 1.2 | 485 | -2.1 | -1.5 |
Chr. 3q27 | ||||||
AP2M1 | 417 | -1.6 | 1.0 | 503 | -2.3 | -3.5 |
TNIK | 143 | 2.1 | 1.1 | 135 | 1.4 | 1.0 |
PRKCI | 68 | 2.1 | 1.2 | 104 | 2.0 | 1.1 |
SI | 1313 | 1.3 | 1.1 | 963 | 1.4 | -2.0 |
EIF4G1 | 292 | -2.5 | -1.6 | 319 | -3.7 | -6.1 |
KLHL6 | 323 | -3.2 | 1.0 | 110 | 1.1 | 1.7 |
FXR1 | 137 | 1.9 | 1.2 | 105 | 2.1 | 2.0 |
Chr. 10q22 | ||||||
MYST4 | 73 | 2.0 | 1.4 | 75 | 2.0 | 1.5 |
RAI17 | 363 | 1.6 | 1.0 | 250 | 1.7 | 2.1 |
- Citation: Zahn A, Moehle C, Langmann T, Ehehalt R, Autschbach F, Stremmel W, Schmitz G. Aquaporin-8 expression is reduced in ileum and induced in colon of patients with ulcerative colitis. World J Gastroenterol 2007; 13(11): 1687-1695
- URL: https://www.wjgnet.com/1007-9327/full/v13/i11/1687.htm
- DOI: https://dx.doi.org/10.3748/wjg.v13.i11.1687