Upregulation of hypoxia inducible factor 1α mRNA is associated with elevated vascular endothelial growth factor expression and excessive angiogenesis and predicts a poor prognosis in gastric carcinoma

Table 2 Relationship between HIF-1α mRNA, VEGF and MVD value and prognosis of gastric carcinoma

Groups	n	Mean survival time (mo)	5-yr survival (%)
HIF-1α mRNA
-	60	127 ± 10.25	82.72
+	58	37 ± 12.65	25.67
VEGF
-	52	117 ± 11.32	75.35
+	66	45 ± 10.82	21.22
MVD (/0.72 mm2)
< 41.5	76	130 ± 10.72	83.75
≥ 41.5	42	43 ± 11.78	20.42