Mechanism of apoptotic effects induced selectively by ursodeoxycholic acid on human hepatoma cell lines

Table 2 Effect of UDCA on expression of bcl-2 and Bax in HepG2, BEL7402 and L-02 (means ± SD, n = 4)

	HepG2 (%)		BEL7402 (%)		L-02 (%)
UDCA (mmol/L)	bcl-2	Bax	bcl-2	Bax	bcl-2	Bax
0 (control)	24.3 ± 2.4	43.0 ± 5.0	21.6 ± 1.8	44.0 ± 4.0	1.0 ± 0.2	62.0 ± 4.0
0.2	19.4 ± 1.5c	42.0 ± 4.0a	20.1 ± 1.9a	48.4 ± 2.5a	1.0 ± 0.1a	61.0 ± 5.0a
0.4	14.2 ± 2.1b	53.6 ± 2.5c	13.5 ± 1.8b	56.0 ± 4.0c	0.8 ± 0.1a	59.0 ± 3.0a
0.8	10.1 ± 1.6b	59.0 ± 3.0b	11.6 ± 2.1b	59.0 ± 3.0b	0.6 ± 0.3a	64.0 ± 4.0a

^aP > 0.05,

^bP < 0.01,

^cP < 0.05, vs control.