Risk factors for Barrett’s oesophagus and oesophageal adenocarcinoma: Results from the FINBAR study

Table 3 Body mass index and weight comparisons between controls and Barrett’s oesophagus and oesophageal adenocarcinoma patients

	Controls	Barrett's oesophagus			Oesophageal adenocarcinoma
	No.	No.	Adjusted1OR (95% CI)	Further adjustedfor GOROR (95% CI)	No.	Adjusted1OR (95% CI)	Further adjustedfor GOROR (95% CI)
Current BMI in tertiles (kg/m2)
< 25.8	86	77	1.00	1.00	115	1.00	1.00
25.8-29.0	87	64	0.75 (0.47 to 1.19)	0.61 (0.36 to 1.03)	54	0.38 (0.24 to 0.62)	0.35 (0.21 to 0.58)
> 29.0	85	82	0.97 (0.61 to 1.52)	0.75 (0.44 to 1.25)	50	0.38 (0.23 to 0.62)	0.33 (0.20 to 0.56)
BMI 5 yr ago in tertiles (kg/m2)
< 25.0	86	75	1.00	1.00	51	1.00	1.00
25.0-28.1	87	78	1.02 (0.65 to 1.61)	0.84 (0.50 to 1.42)	55	1.23 (0.72 to 2.08)	1.74 (0.66 to 1.97)
> 28.1	86	71	0.89 (0.56 to 1.41)	0.85 (0.51 to 1.44)	120	2.70 (1.65 to 4.41)	2.69 (1.62 to 4.46)
BMI age 21 in tertiles (kg/m2)
< 22.1	81	70	1.00	1.00	55	1.00	1.00
22.1-24.1	88	80	0.96 (0.61 to 1.52)	1.17 (0.70 to 1.99)	64	0.97 (0.59 to 1.60)	1.10 (0.65 to 1.85)
> 24.1	84	69	0.83 (0.51 to 1.33)	1.04 (0.61 to 1.79)	96	1.59 (0.97 to 2.59)	1.81 (1.08 to 3.02)
Maximum weight in tertiles (kg)2
< 73	87	72	1.00	1.00	53	1.00	1.00
73-86	91	89	1.21 (0.76 to 1.95)	1.04 (0.61 to 1.79)	67	1.54 (0.90 to 2.61)	1.42 (0.83 to 2.45)
> 86	80	62	0.98 (0.58 to 1.66)	0.91 (0.50 to 1.66)	104	3.44 (1.97 to 5.98)	3.32 (1.88 to 5.86)
Minimum weight in tertiles (kg)2
< 64	108	102	1.00	1.00	79	1.00	1.00
64-70	81	61	0.83 (0.52 to 1.34)	1.00 (0.58 to 1.72)	52	1.10 (0.65 to 1.86)	1.20 (0.70 to 2.08)
> 70	70	60	0.97 (0.57 to 1.64)	1.25 (0.69 to 2.27)	95	2.83 (1.63 to 4.89)	3.22 (1.82 to 5.71)

GOR: gastro-oesophageal reflux; OR: odds ratio; CI: confidence interval.

¹Adjusted for sex, age at interview date, smoking status (never, ex-, current), alcohol intake (grams), years of full-time education and job type (manual, non-manual).

²Also adjusted for height (centimetres). ^bP≤ 0.001.