Risk factors for Barrett’s oesophagus and oesophageal adenocarcinoma: Results from the FINBAR study

Table 1 Characteristics of controls, Barrett’s and oesophageal adenocarcinoma patients

Variables	Controls	Barrett’s oesophagus	P(BO vs controls)	Oesophagealadenocarcinoma	P(OAC vs controls)
Sex , n (%)			0.548		0.992
Male	220 (84.6)	185 (82.6)		192 (84.6)
Female	40 (15.4)	39 (17.4)		35 (15.4)
Age			0.567		0.276
Mean years	63	62.4		64.2
Education			0.013		< 0.001
Years (full-time)	12	11.3		10.7
Job type			0.016		0.013
Manual	119 (48.0)	130 (59.1)		128 (59.5)
Non-manual	129 (52.0)	90 (40.9)		87 (40.5)
Alcohol, n (%)			0.135		0.004
Never	69 (26.5)	57 (25.6)		65 (28.9)
Ever	191 (73.5)	166 (74.4)		160 (71.1)
Mean (grams/d)	26.1	22.3		19.2
GOR frequent, n (%)			< 0.01		< 0.001
Never	211 (81.2)	60 (26.8)		117 (51.5)
Ever	49 (18.8)	164 (73.2)		110 (48.5)
Body mass index			0.895		< 0.001
Mean	27	27		28.7
Fruit			< 0.001		< 0.001
Frequency per week	14.2	11.9		11.2
Vegetables			0.04		0.348
Frequency per week	20	18.7		20.6
Total energy intake (kcal)			0.036		0.023
Mean	2573.9	2727.2		2744.2
Smoking status, n (%)			0.4		< 0.001
Never	102 (40.2)	87 (39.2)		45 (20.4)
Ex-smoker	107 (42.1)	85 (38.3)		99 (44.8)
Current	45 (17.7)	50 (22.5)		77 (34.8)

BO: Barrett’s oesophagus; OAC: oesophageal adenocarcinoma; GOR: gastro-oesophageal reflux.