Malignancy and mortality in a population-based cohort of patients with coeliac disease or ‘gluten sensitivity’

Table 2 Standardised incidence ratio (SIR) of malignancies

	EMA +ve			AGA +ve			AGA +ve, EMA -ve
	n	Expectedn	SIR(95% CI)	n	Expectedn	SIR(95% CI)	n	Expectedn	SIR(95% CI)
All malignancies	24	25.41	0.94 (0.57-1.32)	96	86.13	1.11 (0.89-1.34)	68	37.28	1.82 (1.39-2.26)
All malignancies (> 6 mo after diagnosis)	20	24.26	0.82 (0.46-1.19)	75	86.05	0.87 (0.67-1.07)	52	39.84	1.31 (0.95-1.66)
All malignancies (> 12 mo after diagnosis)	18	24.24	0.74 (0.40-1.09)	67	85.94	0.78 (0.59-0.97)	44	37.15	1.18 (0.83-1.53)
Non-Hodgkin’s lymphoma	2	0.27	7.47 (0.00-17.83)	6	2.59	2.32 (0.46-4.17)	3	0.52	5.76 (0.00-12.28)
Gastrointestinal cancer	4	2.97	1.35 (0.03-2.67)	14	11.70	1.20 (0.57-1.82)	9	5.24	1.72 (0.60-2.84)
Small intestine	1	0.04	23.33 (0.00-69.07)	1	0.14	7.28 (0.00-21.54)	1	0.06	15.51 (0.00-45.90)
Lung cancer	1	2.60	0.39 (0-1.14)	5	9.98	0.50 (0.06-0.94)	4	4.51	0.89 (0.02-1.76)
Breast cancer	4	3.92	1.02 (0.02-2.02)	5	10.53	0.47 (0.06-0.89)	1	4.09	0.24 (0.00-0.72)
Prostate cancer	2	1.12	1.78 (0.00-4.24)	8	6.30	1.27 (0.39-2.15)	3	3.13	0.96 (0.00-2.04)
Liver cancer	2	0.06	31.62 (0.00-75.45)	3	0.60	5.01 (0.00-10.69)	2	0.27	7.48 (0.00-17.86)