Neutrophil depletion-but not prevention of Kupffer cell activation-decreases the severity of cerulein-induced acute pancreatitis

Table 1 Pancreatic injury in control (CONT) mice and mice treated with cerulein (CER)

	CONT	CER
Serum amylase (UI/L)	1582 [1236 - 1850]	19528 [16369 - 26457]	P < 0.0001
Pancreatic water content (% wet weight)	0.74 [0.71 – 0.76]	0.80 [0.78 - 0.83]	P < 0.0001
Pancreatic MPO activity (U/mg tissue dry weight)	322 [125 - 456]	2738 [1978 - 3245]	P = 0.0002
Pancreatic necrosis (%)	1.26 [0.5 – 2.3]	27.7 [24.5 – 35.0]	P = 0.0001

MPO = myeloperoxidase. n ≥ 5 in each group. Data in CER and CONT groups were compared with Mann-Whitney test.