IL-1β activates p44/42 and p38 mitogen-activated protein kinases via different pathways in cat esophageal smooth muscle cells

Figure 1 No increase of COX and iNOS expression levels by IL-1β. (A) The cultured cat ESMCs were treated with IL-1β for 18 h at each dose scale. The COX-1 and COX-2 expression levels were not altered by IL-1β at concentrations up to 50 ng/mL. (B) The IL-1β (25 ng/mL) treatment also failed to elevate the level after 24 h. (C) iNOS expression was unaffected by IL-1β.