STI571 (Glivec) suppresses the expression of vascular endothelial growth factor in the gastrointestinal stromal tumor cell line, GIST-T1

Figure 3 Expression of HIF-1 alpha was determined by flow cytometry. 2 × 10⁶ GIST-T1 cells were treated with/without STI571 as described in “Materials and the methods. A: Control (normal rabbit IgG); B: non-treated (HIF-1 alpha antibody); C: STI571 (1 μg/mL). MFI, mean fluorescent intensity.