Antitumor activity of an hTERT promoter-regulated tumor-selective oncolytic adenovirus in human hepatocellular carcinoma

Figure 2 Selective oncolytic effect of SG300 on HCC cell lines. At MOI = 10, the cell viability was < 30% in HCC cells, but > 68% in normal cells when infected with SG300. The oncolytic effect of SG300 was stronger on HCC cells and weaker on normal cells than that of ONYX-015, being close to that of WAd5. The killing effect of SG300 and ONYX-015 on normal cells became apparent when MOI = 100. —▲—SG300, —□—ONYX-015, —◆—WAd5.