Meta-analysis of short-term outcomes after laparoscopy-assisted distal gastrectomy

Table 3 Morbidity and mortality

Outcome	Type of studiesincluded in themeta-analysis	Trials(n)	LADG		CODG		Pooled resultsOR (95% CI)	Interpretation	Test forheterogeneity
			Events	Patients(n)	Events	Patients(n)
Overall complications	RCTs	4	16	82	30	80	0.41 (0.20, 0.85) Z = 2.41, P = 0.02	L < C	χ2 = 2.52, df = 3 P = 0.47, I2 = 0%
	Overall	13	58	535	97	519	0.54 (0.37, 0.77) Z = 3.37, P < 0.001	L < C	χ2 = 9.11, df = 12 P = 0.69, I2 = 0%
Anastomotic leakage	RCTs	2	0	44	3	43	0.23 (0.02, 2.18) Z = 1.28, P = 0.20	L = C	χ2 = 0.07, df = 1 P = 0.80, I2 = 0%
	Overall	7	2	385	10	365	0.38 (0.12, 1.18) Z = 1.67, P = 0.10	L = C	χ2 = 0.96, df = 6 P = 0.99, I2 = 0%
Anastomotic stenosis	RCTs	2	0	38	2	37	0.31 (0.03, 3.11) Z = 1.00, P = 0.32	L = C	χ2 = 0.00, df = 1 P = 1.00, I2 = 0%
	Overall	5	6	172	5	163	1.11 (0.35, 3.54) Z = 0.18, P = 0.86	L = C	χ2 = 2.01, df = 4 P = 0.73, I2 = 0%
Postoperative ileus	Overall	6	2	267	13	264	0.27 (0.09, 0.84) Z = 2.26, P = 0.02	L < C	χ2 = 1.40, df = 5 P = 0.92, I2 = 0%
Pulmonary complications	RCTs	4	10	82	19	80	0.47 (0.20, 1.12) Z = 1.70, P = 0.09	L = C	χ2 = 1.95, df = 3 P = 0.58, I2 = 0%
	Overall	8	12	260	22	271	0.54 (0.25, 1.15) Z = 1.59, P = 0.11	L = C	χ2 = 3.66, df = 7 P = 0.82, I2 = 0%
Wound infection	RCTs	2	3	54	3	52	0.96 (0.18, 5.01) Z = 0.05, P = 0.96	L = C	χ2 = 0.05, df = 1 P = 1.00, I2 = 0%
	Overall	9	9	448	13	421	0.69 (0.30, 1.57) Z = 0.89, P = 0.37	L = C	χ2 = 3.00, df = 8 P = 0.93, I2 = 0%
Mortality	Overall	2	2	101	3	105	0.67 (0.11, 4.24) Z = 0.43, P = 0.67	L = C	χ2 = 0.19, df = 1 P = 0.66, I2 = 0%

L: Laparoscopy-assisted distal gastrectomy; C: Conventional open distal gastrectomy; OR: Odds ratio; CI: Confidence intervals; RCTs: Randomized controlled trials; df: Degree of freedom.