Sorbitol-based osmotic diarrhea: Possible causes and mechanism of prevention investigated in rats

doi:10.3748/wjg.v12.i47.7635

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Dec 21, 2006 (publication date) through Jan 31, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Dec 21, 2006; 12(47): 7635-7641
Published online Dec 21, 2006. doi: 10.3748/wjg.v12.i47.7635

Table 1 Transit of the marker (phenol red) in the different segments of the intestinal tract during 1 h after the dose ingestion (mean ± SD)

Group	Small intestine				Colon
	1^st quarter	2^nd quarter	3^rd quarter	Last quarter	Proximal
Sorbitol (%)	91.94 ± 8.74	84.56 ± 10.2	69.66 ± 15.42	44.22 ± 19.68	2.48 ± 2.09
S + RG (%)	87.40 ± 9.05	76.39 ± 10.4	56.97 ± 16.04	36.48 ± 17.96	3.07 ± 2.27

Values indicate the amount of marker (phenol red) passing into the following segments, as a percentage of the total marker that entered that particular segment.

Citation: Islam MS, Sakaguchi E. Sorbitol-based osmotic diarrhea: Possible causes and mechanism of prevention investigated in rats. World J Gastroenterol 2006; 12(47): 7635-7641
URL: https://www.wjgnet.com/1007-9327/full/v12/i47/7635.htm
DOI: https://dx.doi.org/10.3748/wjg.v12.i47.7635