Treatment of hepatocellular carcinoma accompanied by portal vein tumor thrombus

Table 3 Radiation for hepatocellular carcinoma with portal vein tumor thrombus

Lead author	Yr	n	Location oftumor thrombus	Treatment	Response rateof PVTT (%)	Median survivaltime (mo)
Chen SC et al[41]	1994	10	Vp2	TACE for liver tumor + Radiation (30-50 Gy) for PVTT	100	-
Tazawa J et al[42]	2001	24	Vp3, 4	TACE for liver tumor + Radiation (50 Gy) for PVTT	50	CR PR; 9.7
						NC PD; 3.8
Yamada K et al[43]	2001	8	Vp3	Radiation (60 Gy) for PVTT followed by TACE for liver tumor	37.5	-
Ishikura S et al[44]	2002	20	Vp3	TACE + Radiation	50	5.3
Yamada K et al[45]	2003	19	Vp3	3-D CRT for PVTT (60 Gy) followed by TACE for liver tumor	57.9	7
Hata M et al[53]	2004	12	Vp3, 4	Proton beam therapy	100	27
				(50-72 Gy)		(24%: 5-YSR)
Nakagawa K et al[46]	2005	52	Vp2, 3, 4	3-D CRT for PVTT (60 Gy)	50	(15.2%; 3-YSR)
Zeng ZC et al[47]	2005	44		Radiation (50 Gy, 36-60)	45.5	8
Kim DY et al[50]	2005	59	Vp3, 4	3-D CRT	45.8	CR PR; 10.7
						NC PD; 5.3
Lin CS et al[48]	2006	43	Vp3, 4	Conventional: 22	Con: 75	Con: 6.0
				3-D CRT: 21	3-D CRT: 83	3-D CRT: 6.7
Hsu WC et al[49]	2006	53	Vp3, 4	3-D CRT and thalidomide	50	-

3-D CRT: Three-dimensional conformal radiation therapy; YSR: Year survival rate.