Acute fatty liver of pregnancy: An update on pathogenesis and clinical implications

Figure 1 Fatty Acid Import into the Mitochondria and Fatty Acid β-oxidation. Long chain fatty acids are actively transported across the plasma membrane, esterified to coenzyme A, carried by fatty acid binding proteins through the cytoplasm to the mitochondria and translocated across the mitochondrial membranes by the carnitine shuttle into the mitochondrial matrix. The fatty acid is subsequently cleaved into two shorter carbon entities by the β-oxidation spiral.