Non-invasive diagnosis of gastric mucosal atrophy in an asymptomatic population with high prevalence of gastric cancer

doi:10.3748/wjg.v12.i44.7172

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Nov 28, 2006 (publication date) through Nov 4, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 28, 2006; 12(44): 7172-7178
Published online Nov 28, 2006. doi: 10.3748/wjg.v12.i44.7172

Table 3 Characteristics of the asymptomatic population samples according to the estimated gastric cancer risk

Characteristics	Estimated gastric cancer risk			Total(n = 536)
Characteristics	Low (A)(n = 115)	Medium (B)(n = 354)	High (C)(n = 67)	Total(n = 536)
Corpus atrophy¹	Absent	Absent	Present
H pylori infection²	Absent	Present	Present or absent
Men, n (%)	46 (40.0)	168 (47.5)	35 (52.2)	249 (46.5)
Age (yr)^a, (mean ± SD)	49.6 ± 22.2	48.6 ± 18.0	61.9 ± 13.3	50.5 ± 19.0
Educational level (yr)^a, (mean ± SD)	8.8 ± 5.2	8.2 ± 4.3	5.8 ± 4.2	8.0 ± 4.6
Rurality, n (%)	27 (23.5)	99 (28.0)	22 (32.8)	148 (27.6)
Living in high-risk counties, n (%)	39 (33.9)	146 (41.2)	24 (35.8)	209 (39.0)
17-Gastrin^a (pmol/L), (mean ± SD)	4.1 ± 6.8	5.6 ± 7.1	14 ± 14.3	6.3 ± 8.8

¹As determined by serum level of PG-1 ≤ 61.5 µg/L and PG-1/PG-2 ratio ≤ 2.2.

²Serology (+) for H pylori (ELISA).

^aSignificant variables in the multivariate analysis (P < 0.05): B vs A: 17-gastrin (OR 1.05); C vs A: sex (OR 2.08); age (OR 1.02); education years (OR 0.9); 17-gastrin (OR 1.13).

Citation: Rollan A, Ferreccio C, Gederlini A, Serrano C, Torres J, Harris P. Non-invasive diagnosis of gastric mucosal atrophy in an asymptomatic population with high prevalence of gastric cancer. World J Gastroenterol 2006; 12(44): 7172-7178
URL: https://www.wjgnet.com/1007-9327/full/v12/i44/7172.htm
DOI: https://dx.doi.org/10.3748/wjg.v12.i44.7172