Relationship between Crohn’s disease, infection with Mycobacterium avium subspecies paratuberculosis and SLC11A1 gene polymorphisms in Sardinian patients

Table 1 Full and reduced logistic regression main effects models for the association between Crohn's disease, MAP infection, and the presence of a number of genetic polymorphisms of the NRAMP1 gene

		Full model		Reduced model2
		Odds Ratio	P	Odds Ratio	P
MAP	Negative	1.01		1.01
	Positive	45.5	< 0.001	42.4	< 0.001
1729 + 55del4	+/+	1.01		1.01
	+/DEL, DEL/DEL	5.6	0.014	5.6	0.011
823 C/T	CC	1.01		1.01
	CT	75.6	0.001	50.8	0.001
D534R	GG	1.01
	GC	1.1	0.913
(-)237C/T	CC	1.01
	CT, TT	0.5	0.350
INT4	GG	1.01
	GC, CC	2.5	0.224
GT (n)	Allele1	1.01
	Allele2	1.2	0.807
	Allele3	0.6	0.673

¹Reference category;

²Model statistics: Likelihood ratio test for equivalence with full model: P = 0.436; Pearson goodness-of-fit test: P = 0.407; Area under Receiver-Operating Characteristic curve: 0.886.