Identification of squamous cell carcinoma associated proteins by proteomics and loss of beta tropomyosin expression in esophageal cancer

Table 1 Mass spectrometric identification and characteristics of the 14 proteins whose expression were subjected to change in SCCE

Polypeptide	Tissue specification	Protein name	Accession numberbased on NCBI	Chromosome	PI/MW	Expression profilingor level
A	Normal	Beta tropomyosin	NM-003289	9p13.2-p13.1	5.5/40.3	Disappearance
B	Normal	Myosin regulatory light chain 2	XM-027060	18p11.31	5.45/17.6	Down Regulation
C	Normal	Myosin light chain 2	NM-000432	16p11.2	5.6/17.6	Down Regulation
D	Normal	Unknown	NC-000963	Map No	5.8/17.6	Down Regulation
E	Normal	Myosin light chain 2	NM-000432	16p11.2	6/17.6	Down Regulation
F	Normal	Peroxiredoxin 2	NM-005809	19p13/2	6.6/26	Down Regulation
G	Normal	Annexin 1	NM-000700	9	7.3/35.5	Down Regulation
1	Tumor	Heat shock protein 70 kD	XM-044201	Unpublish	6/64	Up Regulation
2	Tumor	TPM4-ALK fusion oncoprotein 2	A186109	19p13/1	5.5/32.5	Up Regulation
3	Tumor	Myosin light polypeptide 6	NM-0211019	12p13/3	5.4/20.1	Up Regulation
4	Tumor	Keratin 1	AF304164	12q13	6.9/42.5	Up Regulation
5	Tumor	DNA directed RNA polymerase B (ropB)	NC-000915		6.1/27.2	Up Regulation
6	Tumor	GH16431P	Ay051511		6.6/30.1	Up Regulation
7	Tumor	Calreticulin	NM-004343	19p13/3	5.2/50	Up Regulation