Pathophysiology of pulmonary complications of acute pancreatitis

Table 2 Pathogenic players in respiratory insufficiency

1 Phospholipase A2

2 Trypsin inhibitor

3 FFA/Lipoprotein lipase

4 Complement activation (C5a)

5 MIF

6 IL-6, IL-8, IL-1β

7 NO

8 TNF-α

9 fMet-Leu-Phe (a bacterial wall product)

10 ICAM-1

11 β-2-integrin (CD11b/CD18)

12 Trypsin

13 NF-κB

14 Substance P