Hepatitis B genotypes: Relation to clinical outcome in patients with chronic hepatitis B in Saudi Arabia

Table 1 Biochemical, hematological and virological parameters of all enrolled patients distributed across the four groups

Parameter (mean value)	Group 1(n = 17)	Group 2(n = 22)	Group 3(n = 19)	Group 4(n = 12)	P
ALT (U/L)	41.88	177.7	52	96	0.001
AST (U/L)	22	80	55.3	150	0.001
ALP (U/L)	100	111	116.4	238.8	0.001
INR	1.3	1.1	1.4	1.2	0.003
Bilirubin (μmol/L)	10	13.8	40.4	30	0.001
Albumin (g/L)	40	37.6	28.9	25.4	0.005
WBC (109/L)	7.1	6.1	4.9	7.2	0.160
Hemoglobin (g/L)	125	129.6	118.4	62	0.740
Platelets (109/L)	253	202	121.3	213	0.230
HBV DNA level
< 200 copies/mL	5	2	3	1	NS
200-105 copies/mL	10	8	8	8	NS
> 105 copies/mL	2	12	8	3	NS

ALT: Alanine transaminase; AST: Aspartate transaminase; ALP: Alkaline phosphatase; GGT: Gamma glutamyl transpeptidase; WBC: White blood cells.