Dexamethasone mediates protection against acute pancreatitis via upregulation of pancreatitis-associated proteins

Figure 3 PAP expression is upregulated by dexamethasone: Rats (8/group) were treated with daily saline (white bars) or dexamethasone (grey bars) prior to pancreatitis induction. Pancreata were harvested 24 h after pancreatitis induction and PAP levels were determined by real time PCR and presented as fold change (normalized to β-actin) as described in materials and methods, and described in text as a ratio of PAP mRNA from NaT treated/saline treated pancreas mRNA (^aP < 0.05 vs saline treated controls, Student’s t-test).