Dexamethasone mediates protection against acute pancreatitis via upregulation of pancreatitis-associated proteins

Figure 2 PAP expression was upregulated by treatment of dexamethasone and IL-6: In vitro, dexamethasone (Dex) and IL-6 induced a marked transcription of PAP I, II and III genes in AR42J cells at 24 h when compared with untreated (control) cells. Data represent fold change of untreated/unstimulated cells as determined by real-time PCR analysis (see materials and methods). Bars represent mean ± SD from 3 independent experiments (^aP < 0.05 vs controls, ANOVA, Tukey).