Gastric Cancer
Copyright ©2006 Baishideng Publishing Group Co.
World J Gastroenterol. Nov 14, 2006; 12(42): 6766-6770
Published online Nov 14, 2006. doi: 10.3748/wjg.v12.i42.6766
Figure 1
Figure 1 Metabolism of atofluding to into TFU and 5-FU. The acetyl group on the N1 position of atofluding was hydrolyzed in the presence of H2O into TFU rapidly due to the influence of fluorine on the C5 position. 5-FU was transformed from TFU slowly and continually by the liver microsomal enzymes.