Antioxidants vitamin E and C attenuate hepatic fibrosis in biliary-obstructed rats

Table 3 Histologic fibrosis staging and grading of necroinflammatory activity scores according to Scheuer system at the end of the study (mean ± SE)

parameter	Vit C	Vit E	Vit EC	Sham	Control
Stage	3.2 ± 0.4b	2.5 ± 0.5b	2.4 ± 0.8ab	0.5 ± 0.5	3.1 ± 0.7b
Grade	1.5 ± 0.5d	1.5 ± 0.5d	1.4 ± 0.5d	0.2 ± 0.4	1.9 ± 0.7f

^aP < 0.05 vs control;

^bP < 0.001,

^dP < 0.01,

^fP < 0.001 vs sham.