Inhibition of human gastric carcinoma cell growth by atofluding derivative N3-o-toluyl-fluorouracil

Table 2 Growth inhibitory effects of TFU on SGC-7901 and MKN-45 cells in nude mice (n=8)

Cell line	Dosage(mg/kg)	Body weight(mean ± SD, g)	Tumor weight(mean ± SD, g)	Tumor growthinhibition (%)
SGC-7901
	0	22.12 ± 2.31	2.30 ± 0.67
	25	21.62 ± 1.96	1.21 ± 0.61	30.49
	50	20.28 ± 2.95	0.75 ± 0.17	53.24
	100	18.05 ± 2.40	1.23 ± 0.43	65.98
MKN-45
	0	22.72 ± 1.75	1.84 ± 0.72
	25	21.62 ± 1.96	1.09 ± 0.81	40.76
	50	20.28 ± 2.95	0.71 ± 0.40	61.41
	100	18.75 ± 1.44	0.33 ± 0.49	82.07

Differences were analyzed using the Student’s two-tailed test.