Efficacy of thymosin alpha-1 and interferon alpha in treatment of chronic viral hepatitis B: A randomized controlled study

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Nov 7, 2006 (publication date) through Aug 28, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 7, 2006; 12(41): 6715-6721
Published online Nov 7, 2006. doi: 10.3748/wjg.v12.i41.6715

Table 4 Response to treatment between thymosin-a1 & IFN-a groups

	At the end of therapy OR (95% CI)	At the end of follow-up OR (95% CI)
ALT normalization	0.65 (0.21, 2.01)	3.19 (1.02, 10.61)^a
HBVDNA-negation	0.62 (0.19, 1.94)	3.94 (1.23, 13.69)^b
HBeAg-negation	0.55 (0.17, 1.72)	2.45 (0.77, 8.23)
ALT normal/ HBeAg & HBVDNA-negation	0.55 (0.17, 1.72)	2.45 (0.77, 8.23)

^aP < 0.05,

^bP < 0.01 vs IFN-α.

Citation: You J, Zhuang L, Cheng HY, Yan SM, Yu L, Huang JH, Tang BZ, Huang ML, Ma YL, Chongsuvivatwong V, Sriplung H, Geater A, Qiao YW, Wu RX. Efficacy of thymosin alpha-1 and interferon alpha in treatment of chronic viral hepatitis B: A randomized controlled study. World J Gastroenterol 2006; 12(41): 6715-6721
URL: https://www.wjgnet.com/1007-9327/full/v12/i41/6715.htm
DOI: https://dx.doi.org/10.3748/wjg.v12.i41.6715