Hemodynamic and antifibrotic effects of a selective liver nitric oxide donor V-PYRRO/NO in bile duct ligated rats

Table 1 General characteristics of rats

Characteristics	Sham		BDL		P
	Placebo n = 9	V-PYRRO/NO n = 12	Placebo n = 12	V-PYRRO/NO n = 10
Initial body weight (g)	299 ± 34	274 ± 29	288 ± 56	293 ± 67	NS
Body weight gain (%)	33 ± 21	22 ± 9	14 ± 12a	21 ± 17	0.04
Liver / body weight (%)	2.3 ± 0.4	2.8 ± 0.3	5.9 ± 1.5a	5.6 ± 2.0c	< 0.0001
Ascites score	0	0	0.3 ± 0.9	0	NS

^aP < 0.05 vs sham,

^cP < 0.05 vs V-PYRRO/NO sham; NS: Not significant.