Precore/basal core promoter mutants and hepatitis B viral DNA levels as predictors for liver deaths and hepatocellular carcinoma

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Nov 7, 2006 (publication date) through Nov 29, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Liver Cancer

World J Gastroenterol. Nov 7, 2006; 12(41): 6620-6626
Published online Nov 7, 2006. doi: 10.3748/wjg.v12.i41.6620

Table 2 Demographic and virologic characteristics of precore 1896 mutants

Characteristic	Mutant	Wild type	P
Number	112	270
Age (yr) (mean ± SD)	49.7 ± 14.8	47.3 ± 15.1	0.16
Male/Female	77/35	192/78	0.6
Asian/Non-Asian	99/13	201/69	0.002
Genotype, n (%)			< 0.0001
A	2/93 (2.1)	54/227 (23.8)
B	53/93 (56.9)	39/227 (17.2)
C	38/93 (40.9)	128/227 (56.4)
Baseline HBV-DNA level (mean ± SD, copies/mL)	5.5 ± 2.0 Log₁₀	6.5 ± 2.3 Log₁₀	< 0.0001
HBeAg, n (%)			< 0.0001
+	33/109 (30.1)	161/268 (60.1)
−	76/109 (69.7)	107/268 (39.9)

Citation: Tong MJ, Blatt LM, Kao JH, Cheng JT, Corey WG. Precore/basal core promoter mutants and hepatitis B viral DNA levels as predictors for liver deaths and hepatocellular carcinoma. World J Gastroenterol 2006; 12(41): 6620-6626
URL: https://www.wjgnet.com/1007-9327/full/v12/i41/6620.htm
DOI: https://dx.doi.org/10.3748/wjg.v12.i41.6620