Development and characterization of multidrug resistant human hepatocarcinoma cell line in nude mice

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Nov 7, 2006 (publication date) through Nov 30, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 7, 2006; 12(41): 6614-6619
Published online Nov 7, 2006. doi: 10.3748/wjg.v12.i41.6614

Table 2 Levels of resistance-associated proteins in HepG2 and HepG2/ADM cells (mean ± SD)

Tumor cell	P-gp	MRP	LRP
HepG2	1.00 ± 0.04	0.16 ± 0.10	0.001 ± 0.00
HepG2/ADM	4.68 ± 0.63^b	1.40 ± 0.15^b	0.785 ± 0.04
HepG2/nude	1.00 ± 0.04	0.16 ± 0.08	0.001 ± 0.00
HepG2/ADM/nude	4.73 ± 0.68^d	1.43 ± 0.16^d	0.771 ± 0.02

^bP < 0.01 vs HepG2;

^dP < 0.01 vs HepG2/nude.

Citation: Zhai BJ, Shao ZY, Zhao CL, Hu K, Wu F. Development and characterization of multidrug resistant human hepatocarcinoma cell line in nude mice. World J Gastroenterol 2006; 12(41): 6614-6619
URL: https://www.wjgnet.com/1007-9327/full/v12/i41/6614.htm
DOI: https://dx.doi.org/10.3748/wjg.v12.i41.6614

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