Liver Cancer
Copyright ©2006 Baishideng Publishing Group Co.
World J Gastroenterol. Nov 7, 2006; 12(41): 6614-6619
Published online Nov 7, 2006. doi: 10.3748/wjg.v12.i41.6614
Table 1 Sensitivity of in vitro and in vivo HepG2 and HepG2/ADM tumor cells to chemotherapeutic agents (mean ± SD)
DrugIC50 values (mg/L)
RIaRIb
HepG2HepG2/ADMHepG2/nudeHepG2/ADM/nude
ADM0.02 ± 0.0151.02 ± 0.326b0.16 ± 0.0154.21 ± 0.012d51.0026.31
VCR0.18 ± 0.01110.27 ± 2.415b0.18 ± 0.2111.11 ± 0.075d57.066.17
CDDP0.87 ± 0.0232.03 ± 0.3600.22 ± 0.0231.42 ± 0.032d2.336.45
5-FU9.48 ± 0.11214.16 ± 1.9240.53 ± 0.1122.17 ± 0.6701.494.09