Attenuation of dextran sodium sulphate induced colitis in matrix metalloproteinase-9 deficient mice

Figure 2 Gelatinase Activity in purified Neutrophils. A: Representative zymogram in wild-type (wt) and MMP-9-deficient (KO) animals on d 5 (DSS 5) and 12 (DSS 12) after induction of colitis (n = 15 in each group). Supernatant of HT1080 cells, human recombinants MMP-9 (rMMP9) and MMP-2 (rMMP2) were used as positive controls. HBSS was used as negative control. Pro-MMP-9 was detected in neutrophils from colitic wt animals; B: Quantitative data (^aP < 0.05 vs controls).