Severity of ulcerative colitis is associated with a polymorphism at diamine oxidase gene but not at histamine N-methyltransferase gene

Table 1 HNMT genotypes and allele frequencies among overall UC patients and healthy controls

Genotype	UC patients		Healthy controls		OR (95% CI)	p
	n	% (95% CI)	n	% (95% CI)
C / C	161	82.6 (77.2-87.9)	193	78.8 (73.7-83.9)	1.27 (0.79-2.05)	0.33
C / T	32	16.4 (11.2-21.6)	48	19.6 (14.6-24.6)	0.75 (0.45-1.23)	0.34
T / T	2	1.0 (0-2.4)	4	1.6 (0-3.2)	0.60 (0.13-2.85)	0.50
Total subjects	195		245
C allele	354	90.8 (87.9-93.6)	434	88.6 (85.8-91.4)	1.27 (0.80-2.02)	0.29
T allele	36	9.2 (6.4-12.1)	56	11.4 (8.6-14.2)
Total alleles	390		490