Role of gastric oxidative stress and nitric oxide in formation of hemorrhagic erosion in rats with ischemic brain

Table 1 Influences of gastric juice on various gastric biomedical parameters in sham operation and BCAL rats

	Acid back-diffusion(μEq/stomach)	Glutathione(μmol/gtissue)	Lipid peroxide(nmol MDA/gtissue)	Hemoglobin(mg/stomach)	Erosion(areamm2)	Histologicalscore
Sham operation
Saline	56.0 ± 6.0	3.0 ± 0.4	36.1 ± 4.5	0.1 ± 0.1	0.3 ± 0.2	0.3 ± 0.1
Gastric juice	-135.6 ± 4.4	2.6 ± 0.3	50.1 ± 6.4	0.3 ± 0.1	0.4 ± 0.8	0.7 ± 0.3
BCAL
Saline	30.2 ± 4.1a	2.1 ± 0.3a	88.1 ± 3.4a	0.8 ± 0.2a	8.2 ± 0.9a	1.8 ± 0.3a
Gastric juice	-250.2 ± 10.4c	1.4 ± 0.2 c	137.6 ± 10.4c	2.0 ± 0.4c	40.2 ± 7.1c	4.5 ± 0.7c

Data are means±SE (N = 8). Significant differences are analyzed by using ANOVA.

^aP < 0.05 vs saline treated sham operation group;

^cP <  0.05 vs gastric juice treated sham operation group, BCAL= bilateral carotid artery ligation, MDA = malonedialdehyde.