Long-term lamivudine treatment for chronic hepatitis B in Japanese patients: A project of Kyushu University Liver Disease Study

Table 2 Virological response of 318 patients with chronic HBV infection treated with lamivudine (mean± SD)

Characteristics	Virological response		P
	No	Yes
	n = 288	n = 30
Number of men (%)	207 (71.9)	24 (80.0)	0.4624
Age (yr)	47.9 ± 11.4	46.9 (22-73)	0.6453
Number of cirrhosis (%)	90 (31.2)	12 (40.0)	0.4403
Baseline laboratory data
Total bilirubin (mg/dL)	1.3 ± 1.5	1.1 ± 0.6	0.6895
Albumin (g/dL)	3.9 ± 0.6	3.8 ± 0.6	0.2381
Platelet count (x 104/μL)	14.3 ± 5.9	13.2 ± 5.8	0.2624
Number of HBeAg positivity (%)	147 (51.0)	26 (86.7)	0.0004
HBV-DNA1	6.6 ± 1.2	7.7 ± 0.7	< 0.0001

ALT, alanine aminotransferase; HBeAg, hepatitis B e antigen; SD, standard deviation ¹Logarithmic transformed copies/mL