Hepatic progenitor cells in human liver tumor development

Figure 2 Hematoxylin-eosin stained section of a hepatocellular carcinoma, which suggests that the tumor consists of mature hepatocytes (A). However, the staining for the hepatic progenitor cell marker cytokeratin 7 (B and C) shows the presence of hepatic progenitor cells (arrowheads) and intermediate hepatocyte-like cells (arrows) distributed in a “starry sky” pattern against a background of mature hepatocytes. Original magnification: x 100 (A and B) and x 200 (C).