Aberrant cytological localization of p16 and CDK4 in colorectal epithelia in the normal adenoma carcinoma sequence

doi:10.3748/wjg.v12.i39.6391

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Oct 21, 2006 (publication date) through Jul 23, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 21, 2006; 12(39): 6391-6396
Published online Oct 21, 2006. doi: 10.3748/wjg.v12.i39.6391

Table 3 Relationship between CDK4 subcellular expression pattern and clinicopathological features

	CDK4 subcellular pattern
Clinicopathological feature	n	C/N	C
Dukes’ stage
A	22	4	18
B	22	4	18
C	30	7	23
Histological grade
I	24	4	20
II	41	10	31
III	9	1	8
Total	74	15	59

C/N: cytoplasm/nucleus. There was no significant correlation between CDK4 subcellular expression pattern and the Dukes’ stage (P = 0.844) or histological grade (P = 0.584) of the carcinoma.

Citation: Zhao P, Mao X, Talbot IC. Aberrant cytological localization of p16 and CDK4 in colorectal epithelia in the normal adenoma carcinoma sequence. World J Gastroenterol 2006; 12(39): 6391-6396
URL: https://www.wjgnet.com/1007-9327/full/v12/i39/6391.htm
DOI: https://dx.doi.org/10.3748/wjg.v12.i39.6391