Aberrant cytological localization of p16 and CDK4 in colorectal epithelia in the normal adenoma carcinoma sequence

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Oct 21, 2006 (publication date) through Dec 25, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 21, 2006; 12(39): 6391-6396
Published online Oct 21, 2006. doi: 10.3748/wjg.v12.i39.6391

Table 1 Relationship between the subcellular expression pattern of p16 or CDK4 and the histology of epithelia of normal-adenoma-carcinoma sequence

	Subcellular expression pattern
Histology	Total	C/N	C
p16
Normal	42	40	2
Adenoma	43	32	11
Carcinoma	73	27	46
P < 0.001
CDK4
Normal	38	29	9
Adenoma	43	10	33
Carcinoma	74	15	59
P < 0.001

C/N: Cytoplasm/nucleus.

Citation: Zhao P, Mao X, Talbot IC. Aberrant cytological localization of p16 and CDK4 in colorectal epithelia in the normal adenoma carcinoma sequence. World J Gastroenterol 2006; 12(39): 6391-6396
URL: https://www.wjgnet.com/1007-9327/full/v12/i39/6391.htm
DOI: https://dx.doi.org/10.3748/wjg.v12.i39.6391