Expression of p53, Bax and Bcl-2 proteins in hepatocytes in non-alcoholic fatty liver disease

doi:10.3748/wjg.v12.i38.6198

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Oct 14, 2006 (publication date) through Jul 18, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 14, 2006; 12(38): 6198-6202
Published online Oct 14, 2006. doi: 10.3748/wjg.v12.i38.6198

Table 3 Correlation of biochemical degree of liver damage and expression of pro- and anti-apoptotic proteins in hepatocytes with the stage of liver steatosis

	r
ALT	0.6^b
AST	0.37^b
ALP	0.55^b
GGT	0.53^b
Total protein	-0.54^b
Albumines	-0.34^b
Bax NSH¹	NS³
Bax SH²	NS³
p53 NSH¹	0.49^b
p53 SH²	0.54^b
Bcl2 NSH¹	-0.43^b
Bcl2 SH²	NS³

¹Non-steatosed hepatocytes;

²Steatosed hepatocytes;

³Non-statistical correlation.

^bP < 0.01 vs the stage of liver steatosis (non-parametrical Spearman test).

Citation: Panasiuk A, Dzieciol J, Panasiuk B, Prokopowicz D. Expression of p53, Bax and Bcl-2 proteins in hepatocytes in non-alcoholic fatty liver disease. World J Gastroenterol 2006; 12(38): 6198-6202
URL: https://www.wjgnet.com/1007-9327/full/v12/i38/6198.htm
DOI: https://dx.doi.org/10.3748/wjg.v12.i38.6198