Expression of p53, Bax and Bcl-2 proteins in hepatocytes in non-alcoholic fatty liver disease

Table 2 Percentage of hepatocytes containing pro- and antiapoptotic proteins depending on the stage of liver steatosis (mean ± SD, %)

	Total	GroupI	Group II	Group III
Bax NSH 1	59 ± 21	66 ± 15	52 ± 27	57 ± 19
Bax SH 2	68 ± 23	71 ± 21	63 ± 28	67 ± 18
p53 NSH 1	24 ± 12	18 ± 14d	21 ± 9 d	35 ± 9
p53 SH 2	22 ± 17	14 ± 18bd	20 ± 13d	33 ± 14
Bcl2 NSH 1	55 ± 26	77 ± 21bd	46 ± 20	49 ± 27
Bcl2 SH 2	44 ± 27	52 ± 37	42 ± 20	41 ± 24

¹Non-steatosed hepatocytes;

²Steatosed hepatocytes.

^bP < 0.01 vs group II,

^dP < 0.01 vs group III (non-parametrical Student’s-t test).