Increased DNA binding activity of NF-kB, STAT-3, SMAD3 and AP-1 in acutely damaged liver

doi:10.3748/wjg.v12.i37.5995

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Oct 7, 2006 (publication date) through Jan 11, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 7, 2006; 12(37): 5995-6001
Published online Oct 7, 2006. doi: 10.3748/wjg.v12.i37.5995

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Figure 4 Binding activity of STAT-3 in acute liver damage. Wistar rats were intoxicated acutely with CCl₄ and then sacrificed at different time points. Nuclear proteins were extracted from the livers and Gel-shift assay was performed for STAT-3. A: Binding DNA activity of STAT-3 after CCl₄ intoxication; B: supershift assay similar using 6-h sample; C: densitometric analysis of results of EMSA assay.

Citation: Salazar-Montes A, Ruiz-Corro L, Sandoval-Rodriguez A, Lopez-Reyes A, Armendariz-Borunda J. Increased DNA binding activity of NF-_kB, STAT-3, SMAD3 and AP-1 in acutely damaged liver. World J Gastroenterol 2006; 12(37): 5995-6001
URL: https://www.wjgnet.com/1007-9327/full/v12/i37/5995.htm
DOI: https://dx.doi.org/10.3748/wjg.v12.i37.5995