Sustained low diffusing capacity in hepatopulmonary syndrome after liver transplantation

Table 2 Lung function test and blood gas analysis before and after liver transplantation (LT) (mean ± SE)

	HPS1			Non-HPS1
Parameter	Pre-LT	Mid-term Post-LT	Long-term Post-LT	Pre-LT	Mid-term Post-LT
FEV12 (% pred)	89 ± 7	92 ± 8	87 ± 9	90 ± 4	89 ± 4
FVC 3 (% pred)	97 ± 6	100 ± 7	93 ± 11	89 ± 3	88 ± 3
FEV12/FVC3 4 (%)	72 ± 4	77 ± 5	74 ± 5	76 ± 2	76 ± 2
TLC4 (% pred)	100 ± 7	100 ± 9	99 ± 9	96 ± 2	93 ± 18
DLCO5 (mL/min/mmHg)	16.8 ± 3.4c	16.6 ± 3.5	16.9 ± 3.3	23.1 ± 2.1	20.7 ± 3.5
DLCO5 (% pred)	54 ± 9c	53 ± 8	56 ± 7	85 ± 3	79 ± 3
KCO6 (%pred)	59 ± 10c	54 ± 6	60 ± 7	91 ± 3	86 ± 4
VE7 (l/min)	10.3 ± 1.2	7.4 ± 0.4a	na13	10.3 ± 1.0	8.4 ± 0.6
VO28 (mL/min)	263.7±22.8	247.0 ± 26.2a	na13	270.3 ± 17.6	254.3 ± 13.2
Hemoglobin (g/L)	111 ± 22	121 ± 20	134 ± 21	104 ± 18	114 ± 16
PHa9	7.45 ± 0.02	7.39 ± 0.01a	7.42 ± 0.01	7.47 ± 0.01	7.41 ± 0.01a
PaO210 (mmHg)	71 ± 8c	91 ± 3a	87 ± 5a	94 ± 4	94 ± 2
PaCO211 (mmHg)	28 ± 2	36 ± 1a	34 ± 0a	31 ± 1	35 ± 1a
AaPO212 (mmHg)	43 ± 10c	14 ± 3a	23 ± 5a	19 ± 3	14 ± 2

¹Hepatopulmonary syndrome;

²Forced expiratory volume at 1 s;

³Forced vital capacity;

⁴Total lung capacity;

⁵Single-breath carbon monoxide diffusing capacity;

⁶carbon monoxide diffusing capacity normalized per liter alveolar volume;

⁷Minute ventilation;

⁸Oxygen uptake;

⁹Arterial pH;

¹⁰Partial pressure of arterial oxygen;

¹¹Partial pressure of arterial carbon dioxide;

¹²Alveolar to arterial oxygen partial pressure gradient;

¹³Not available.

^aP < 0.05 vs pre-LT;

^cP < 0.05 vs non-HPS.