Luminal oxidants selectively modulate electrogenic ion transport in rat colon

doi:10.3748/wjg.v12.i34.5523

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Sep 14, 2006 (publication date) through Nov 5, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 14, 2006; 12(34): 5523-5527
Published online Sep 14, 2006. doi: 10.3748/wjg.v12.i34.5523

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Figure 3 cAMP-activated secretion is blocked by luminal H₂O₂. Incubation of rat distal colon with 10 mmol/L H₂O₂ for 30 min (white circles; n = 6) inhibited the rise in Isc caused by 10 μmol/L forskolin added at time 0 (control in black circles; n = 6; P < 0.01) in white circles, n = 8) and suppressed the secretory response caused by ClT added at time 0 (in black circles, n = 8; P < 0.001 between groups).

Citation: Mayol JM, Adame-Navarrete Y, Alarma-Estrany P, Molina-Roldan E, Huete-Toral F, Fernandez-Represa JA. Luminal oxidants selectively modulate electrogenic ion transport in rat colon. World J Gastroenterol 2006; 12(34): 5523-5527
URL: https://www.wjgnet.com/1007-9327/full/v12/i34/5523.htm
DOI: https://dx.doi.org/10.3748/wjg.v12.i34.5523