Intensity-modulated radiation therapy with concurrent chemotherapy for locally advanced cervical and upper thoracic esophageal cancer

doi:10.3748/wjg.v12.i34.5501

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Sep 14, 2006 (publication date) through Nov 26, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 14, 2006; 12(34): 5501-5508
Published online Sep 14, 2006. doi: 10.3748/wjg.v12.i34.5501

Table 1 Patient and treatment characteristics for the 7 patients with cervical and upper thoracic esophageal cancer

PatientNo.	Tumordistancefrom UES (cm)	Stage	Inductionchemotherapy	Concurrentchemotherapy	XRT dose(GTV)	XRT dose(CTV)	XRT dose(supraclavical regions)
1	2	T₃N₁M₀		5-FU, CDDP	64.8 Gy (2.31 Gy/f)	50.4 Gy (1.8 Gy/f)	50.4 Gy (1.8 Gy/f)
2	0	T₂N₁M₀		5-FU, paclitaxel	59.9 Gy, (2.14 Gy/f)	50.4 Gy (1.8 Gy/f)	0
3	0	T₃N₁M₀		5-FU, CDDP	64.8 Gy (1.8 Gy/f × 8, 2.21 Gy × 21)	51.7 Gy (1.53 Gy/f × 8, 1.88 Gy × 21)	46 Gy (1.36 Gy/f × 8, 1.67 Gy × 21)
4	6	T₃N₀M₀		5-FU, paclitaxel	59.4 Gy (1.8 Gy/f)	59.4 Gy (1.8 Gy/f)	0
5	0	T₄N₁M₀		5-FU, CBP, docetaxel	66 Gy (2.0 Gy/f)	66 Gy (2.0 Gy/f)	0
6	2.5	T₄N₁M₀	CBP, paclitaxel	CBP, paclitaxel	66 Gy (2.0 Gy/f)	56 Gy (1.7 Gy/f)	56 Gy (1.7 Gy/f)
7	0	T₄N₀M₀		5-FU, CDDP	66 Gy (2.0 Gy/f)	60 Gy (1.8 Gy/f)	60 Gy (1.8 Gy/f)

CBP: Carboplatin; CDDP: Cisplatin; CTV: Clinical tumor volume; GTV: Gross tumor volume; f: Fraction; UES: Upper esophageal sphincter; XRT: Radiotherapy

Citation: Wang SL, Liao Z, Liu H, Ajani J, Swisher S, Cox JD, Komaki R. Intensity-modulated radiation therapy with concurrent chemotherapy for locally advanced cervical and upper thoracic esophageal cancer. World J Gastroenterol 2006; 12(34): 5501-5508
URL: https://www.wjgnet.com/1007-9327/full/v12/i34/5501.htm
DOI: https://dx.doi.org/10.3748/wjg.v12.i34.5501