First-line eradication of H pylori infection in Europe: A meta-analysis based on congress abstracts, 1997-2004

Table 3 Changes over time of the eradication rates of PPI-based one-triple therapies between 1997-2004

Yearreferences	Cases (n)	Studies (n)	Treatmentarms (n)	PER (%)	95% CI	P1	References
1997	3216	16	34	80.2	75.8-84.7		12,13,49,58,59,61-65,71-73,77,78,85
1998	1117	11	18	82.0	76.4-87.4	0.59	15,17,21-23,34-36,39
1999	1771	9	14	77.2	71.6-82.7	0.34	24-26,28,40,41,60,67,74
2000	1683	10	13	82.1	78.0-86.1	0.56	27,29,30,37,38,42,43,50,70
2001	1002	8	11	80.7	73.4-87.9	0.9	51-54,68,69,75,84
2002	904	4	7	87.1	80.8-93.4	0.12	41,55,57,76
2003	553	2	4	78.2	67.2-89.4	0.67	45,46
2004	468	3	5	82.6	73.5-91.6	0.65	47,48,56

¹P: 1997 vs other years; P = 0.04 < 0.05 2002 vs 1999; no other significant difference in between-year comparisons; Test of homogeneity: 1997, χ² = 9.98, P = 0.19; 1998, χ² = 0.71, P = 0.39; 1999, χ² = 3.0, P = 0.08; 2000, χ² = 5.17, P = 0.15; 2001, χ² = 0.15, P = 0.72; 2002, χ² = 0.2, P = 0.7; 2003, χ² = 0.14, P = 0.8; 2004, χ² = 0.14 , P = 0.8.