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©2006 Baishideng Publishing Group Co.
World J Gastroenterol. Sep 7, 2006; 12(33): 5301-5305
Published online Sep 7, 2006. doi: 10.3748/wjg.v12.i33.5301
Published online Sep 7, 2006. doi: 10.3748/wjg.v12.i33.5301
Table 2 Clinical Characteristics of 28 patients with chronic hepatitis B before and after long-term treatment of lamivudine
No. | Before treatment | After treatment | 3Sequencing | ||||||
AST/ALT (IU/L) | HBeAg/anti-HBe | 1HBV-DNA | 2Nest-PCR | AST/ALT (IU/L) | HBeAg/anti-HBe | 1HBV-DNA | Nest-PCR | ||
1 | 61/62 | -/+ | 39.93 | - | 29/16 | -/+ | 0.25 | V | V |
2 | 31/43 | +/- | 3574.29 | V | 29/54 | +/- | 4400.65 | M | V |
3 | 85/86 | -/+ | 348.66 | - | 20/11 | -/+ | 0.20 | - | W |
4 | 45/90 | -/+ | 8.50 | - | 23/22 | -/+ | 0.03 | - | W |
5 | 74/75 | -/+ | 256.99 | I | 63/38 | -/+ | 0.01 | I | I |
6 | 82/163 | -/+ | 1596.12 | - | 38/64 | -/+ | 3356.38 | V | V |
7 | 37/43 | +/- | 13.07 | - | 25/39 | +/- | 0.26 | - | W |
8 | 26/62 | -/+ | 49.16 | - | 24/40 | -/+ | 0.03 | - | W |
9 | 82/102 | -/+ | 3313.93 | - | 29/17 | -/+ | 0.60 | V | W |
10 | 40/59 | +/- | 546.76 | I | 24/28 | -/+ | 0.11 | M | I |
11 | 117/232 | +/- | 49.50 | I | 26/27 | +/- | 346.96 | M | I |
12 | 46/61 | -/+ | 47.40 | - | 24/32 | -/+ | 0.06 | V | V |
13 | 72/107 | -/+ | 5.37 | M | 66/92 | -/+ | 2389.09 | M | V |
14 | 155/159 | +/- | 2325.13 | I | 22/14 | +/- | 0.10 | M | W |
15 | 65/54 | -/+ | 1461.13 | - | 42/29 | -/+ | 0.12 | V | W |
16 | 133/157 | +/- | 7943.81 | I | 73/64 | +/+ | 2.05 | I | I |
17 | 107/146 | -/+ | 23.13 | M | 151/232 | -/+ | 59.94 | M | V |
18 | 35/48 | +/- | 1666.59 | - | 22/21 | +/- | 0.15 | - | W |
19 | 247/183 | +/- | 9336.17 | I | 27/14 | +/- | 0.01 | I | W |
20 | 45/56 | -/+ | 219.58 | - | 28/38 | -/+ | 0.03 | - | W |
21 | 109/186 | -/+ | 61.27 | - | 30/48 | -/+ | 2.91 | M | I |
22 | 173/335 | +/- | 11.98 | - | 29/31 | +/- | 0.03 | M | V |
23 | 51/81 | -/+ | 1403.11 | I | 28/42 | -/+ | 303.09 | I | I |
24 | 43/68 | +/- | 365.07 | - | 22/27 | +/- | 1.28 | V | V |
25 | 45/57 | +/- | 7530.63 | I | 30/25 | +/- | 6228.83 | I | I |
26 | 130/286 | -/+ | 126.67 | - | 21/32 | -/+ | 1.46 | I | I |
27 | 64/91 | +/- | 4700.63 | I | 52/73 | +/- | 6.12 | I | I |
28 | 88/164 | -/+ | 0.38 | - | 30/38 | -/+ | 0.07 | - | W |
- Citation: Lee CZ, Lee HS, Huang GT, Yang PM, Sheu JC. Detection of YMDD mutation using mutant-specific primers in chronic hepatitis B patients before and after lamivudine treatment. World J Gastroenterol 2006; 12(33): 5301-5305
- URL: https://www.wjgnet.com/1007-9327/full/v12/i33/5301.htm
- DOI: https://dx.doi.org/10.3748/wjg.v12.i33.5301