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©2006 Baishideng Publishing Group Co.
World J Gastroenterol. Sep 7, 2006; 12(33): 5281-5286
Published online Sep 7, 2006. doi: 10.3748/wjg.v12.i33.5281
Published online Sep 7, 2006. doi: 10.3748/wjg.v12.i33.5281
Table 3 Possible mutations of Mlh3 in familial esophageal cancer
| Exon | Nucleotide | Amino | Family | Family | Cosegregation | Frequency in | Frequency in sporadic | Frequency in normal |
| change1 | change | type | FEC n (%) | EC n (%) | control n (%) | |||
| 1 | A2173C | Asn725His | 9 | MCR | Yes | 4/66 (6.1) | 0/94 (0) | 0/96 (0) |
| 1 | C2825T | Thr9421Ile | 10 | TCR | Yes | 3/66 (4.5) | 1/95 (1.0) | 0/96 (0) |
| 7 | T3826C | Trp1276Arg | 1 | TCR | No | 3/66 (4.5) | 0/96 (0) | 0/96 (0) |
| 12 | G4335A | Gln1445Glu | 7 | MCR | No | 6/66 (9.1) | 0/95 (0) | 0/96 (0) |
- Citation: Liu HX, Li Y, Jiang XD, Yin HN, Zhang L, Wang Y, Yang J. Mutation screening of mismatch repair gene Mlh3 in familial esophageal cancer. World J Gastroenterol 2006; 12(33): 5281-5286
- URL: https://www.wjgnet.com/1007-9327/full/v12/i33/5281.htm
- DOI: https://dx.doi.org/10.3748/wjg.v12.i33.5281