5-Fluorouracil-related enhancement of adenoviral infection is Coxsackievirus-adenovirus receptor independent and associated with morphological changes in lipid membranes

Figure 3 Dependence of adenoviral efficacy on the sequencing of 5-FU and virus administration to the SW480 cells. Two h postincubation with the drug at the indicated concentrations, the drug was removed and the cells were infected with the adenoviral construct Ad-GFP (A). Alternatively, the cells were infected with the virus in combination with 5-FU (B). The number of green cells was counted after 24, 48 and 72 h infection. The reported data points are the average of three experiments and the standard deviation values were in the range of 10%-15% (the error bars were not reported for clarity).