Effect of Fructus Psoraleae on motility of gallbladder isolated smooth muscle strips from guinea pigs

Table 2 Effect of Fructus Psoraleae on the contractile amplitude (mm) of isolated gallbladder muscle strip after pretreated with antagonists (means ± SD)

Amplitude (mm)	Fructus psoraleae (g/L)
	0	0.1	0.3	1	3	10	20
Pso	4.54 ± 0.64	4.23 ± 0.78	4.24 ± 0.84	4.07 ± 0.72	3.71 ± 0.59a	2.36 ± 0.77d	1.72 ± 0.74d
Ben + Pso	4.70 ± 0.57	4.43 ± 0.80	4.19 ± 0.88	4.09 ± 0.97	3.93 ± 0.97	3.55 ± 0.93a	2.37 ± 0.83d
Phe + Pso	4.71 ± 1.37	4.47 ± 1.42	4.64 ± 1.32	4.49 ± 1.35	4.17 ± 1.41	3.36 ± 1.43a	2.15 ± 0.65d
4-DAMP + Pso	4.91 ± 0.60	4.58 ± 0.71	4.23 ± 0.60	4.27 ± 0.84	3.84 ± 0.81a	3.70 ± 1.28b	2.34 ± 1.07d
Hex + Pso	5.48 ± 1.57	5.13 ± 1.64	5.34 ± 1.60	4.86 ± 1.63	4.80 ± 1.46	3.43 ± 1.10b	1.93 ± 1.02d
Ido + Pso	5.40 ± 1.30	5.01 ± 1.37	4.83 ± 1.33	4.62 ± 1.42	4.16 ± 1.29	3.39 ± 1.48b	2.24 ± 1.25d
Iso + Pso	4.47 ± 1.23	4.42 ± 1.37	4.60 ± 1.56	4.29 ± 1.32	4.00 ± 1.08	3.98 ± 1.74	2.80 ± 1.57b

^aP < 0.05,

^bP < 0.01,

^dP < 0.001 vs control (under 1-g initial load the gallbladder spontaneous mean contraction amplitude when Fructus Psoraleae was 0 g/L ) ( n = 8).